Anticancer sustained-release injection containing octadecyl dimethyl-4-piperidine phosphate

A sustained release anti-cancer injection with perifosine consists of the perifosine with effective anti-cancer amount and an amphiphilic block copolymer hydrogel, wherein, part or the whole of perifosine is encapsulated in a sustained release microsphere and exists singly in the form of the sustained release microsphere or microsphere and micro-powder in the sustained release injection. The amphiphilic block copolymer hydrogel is selected from PLGA-polyethylene glycol-PLGA, sustained release gel has temperature-sensitive gelation property, and the sustained release gel is flowable fluid in an environment below body temperature and can automatically change into biodegradable and absorbable non-flowable water-insoluble gel in bodies of warm-blooded animals, thus causing the drug to be slowly released in the local part of tumor; the sustained release microsphere is favorable to the stable and sustained release of the drug, the dual sustained release is beneficial to controlling tumor cells in dormancy stage and