Non-virus non-structural protein foot-and-mouth disease vaccine and preparation thereof

The invention discloses a method for preparing a foot and mouth disease vaccine. The preparation method comprises the steps that monoclonal antibodies of non-structure protein of foot and mouth disease virus is used for removing non-structure protein of foot and mouth disease virus in a target objec...

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Hauptverfasser: XIE BAOXIA, LI YONGLIANG, LI PINGHUA, CHEN YINGLI, CAO YIMEI, GUO JIANHONG, BAO HUIFANG, XIE QINGGE, LIU ZAIXIN, LU ZENGJUN, SUN PU, TIAN MEINA
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creator XIE BAOXIA
LI YONGLIANG
LI PINGHUA
CHEN YINGLI
CAO YIMEI
GUO JIANHONG
BAO HUIFANG
XIE QINGGE
LIU ZAIXIN
LU ZENGJUN
SUN PU
TIAN MEINA
description The invention discloses a method for preparing a foot and mouth disease vaccine. The preparation method comprises the steps that monoclonal antibodies of non-structure protein of foot and mouth disease virus is used for removing non-structure protein of foot and mouth disease virus in a target object which is then prepared into the foot and mouth disease vaccine, wherein, the target object is a foot and mouth disease virus culture or a gene engineering expression product comprising the non-structure protein of foot and mouth disease virus and structure protein of foot and mouth disease virus.The reliability is greatly improved when infected animals are distinguished from immune animals in vaccine immunization animals using the foot and mouth disease vaccine of the invention; in addition,the method for preparing the foot and mouth disease vaccine of virus-free non-structure protein is simple, convenient and effective without extra expensive equipment and can be applied to applicationon a large scale. Therefore
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The preparation method comprises the steps that monoclonal antibodies of non-structure protein of foot and mouth disease virus is used for removing non-structure protein of foot and mouth disease virus in a target object which is then prepared into the foot and mouth disease vaccine, wherein, the target object is a foot and mouth disease virus culture or a gene engineering expression product comprising the non-structure protein of foot and mouth disease virus and structure protein of foot and mouth disease virus.The reliability is greatly improved when infected animals are distinguished from immune animals in vaccine immunization animals using the foot and mouth disease vaccine of the invention; in addition,the method for preparing the foot and mouth disease vaccine of virus-free non-structure protein is simple, convenient and effective without extra expensive equipment and can be applied to applicationon a large scale. 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The preparation method comprises the steps that monoclonal antibodies of non-structure protein of foot and mouth disease virus is used for removing non-structure protein of foot and mouth disease virus in a target object which is then prepared into the foot and mouth disease vaccine, wherein, the target object is a foot and mouth disease virus culture or a gene engineering expression product comprising the non-structure protein of foot and mouth disease virus and structure protein of foot and mouth disease virus.The reliability is greatly improved when infected animals are distinguished from immune animals in vaccine immunization animals using the foot and mouth disease vaccine of the invention; in addition,the method for preparing the foot and mouth disease vaccine of virus-free non-structure protein is simple, convenient and effective without extra expensive equipment and can be applied to applicationon a large scale. Therefore</abstract><oa>free_for_read</oa></addata></record>
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language chi ; eng
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Non-virus non-structural protein foot-and-mouth disease vaccine and preparation thereof
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