Purification method of follicle stimulating hormone
The invention provides a purification method for preparing follicle-stimulating hormone FSH. The method comprises the steps as follows: (A) a raw material containing the FSH is contacted with an antibody, wherein, the raw material contains luteinizing hormone LH and/or chorionic gonadotropin CG as i...
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| creator | YAN HUIMIN JI BIN JIN CANHUANG JI XIAOMING |
| description | The invention provides a purification method for preparing follicle-stimulating hormone FSH. The method comprises the steps as follows: (A) a raw material containing the FSH is contacted with an antibody, wherein, the raw material contains luteinizing hormone LH and/or chorionic gonadotropin CG as impurities, and the antibody is an antibody which specifically combines the LH and/or the CG but not crossly react with the FSH basically, thereby making the antibody form an antigen-antibody compound with the LH and/or the CG; (B) the formed antigen-antibody compound is removed from the raw material, thereby obtaining purified FSH. The invention also provides a method for preparing a drug composition containing the FSH. |
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The method comprises the steps as follows: (A) a raw material containing the FSH is contacted with an antibody, wherein, the raw material contains luteinizing hormone LH and/or chorionic gonadotropin CG as impurities, and the antibody is an antibody which specifically combines the LH and/or the CG but not crossly react with the FSH basically, thereby making the antibody form an antigen-antibody compound with the LH and/or the CG; (B) the formed antigen-antibody compound is removed from the raw material, thereby obtaining purified FSH. The invention also provides a method for preparing a drug composition containing the FSH.</description><language>chi ; eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120104&DB=EPODOC&CC=CN&NR=101307103B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120104&DB=EPODOC&CC=CN&NR=101307103B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YAN HUIMIN</creatorcontrib><creatorcontrib>JI BIN</creatorcontrib><creatorcontrib>JIN CANHUANG</creatorcontrib><creatorcontrib>JI XIAOMING</creatorcontrib><title>Purification method of follicle stimulating hormone</title><description>The invention provides a purification method for preparing follicle-stimulating hormone FSH. 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The invention also provides a method for preparing a drug composition containing the FSH.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAOKC3KTMtMTizJzM9TyE0tychPUchPU0jLz8nJTM5JVSguycwtzQFK56UrZOQX5ebnpfIwsKYl5hSn8kJpbgYlN9cQZw_d1IL8-NTigsTk1LzUknhnP0MDQ2MDc0MDYycnY6IUAQCOQC1Y</recordid><startdate>20120104</startdate><enddate>20120104</enddate><creator>YAN HUIMIN</creator><creator>JI BIN</creator><creator>JIN CANHUANG</creator><creator>JI XIAOMING</creator><scope>EVB</scope></search><sort><creationdate>20120104</creationdate><title>Purification method of follicle stimulating hormone</title><author>YAN HUIMIN ; JI BIN ; JIN CANHUANG ; JI XIAOMING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN101307103BB3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>YAN HUIMIN</creatorcontrib><creatorcontrib>JI BIN</creatorcontrib><creatorcontrib>JIN CANHUANG</creatorcontrib><creatorcontrib>JI XIAOMING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YAN HUIMIN</au><au>JI BIN</au><au>JIN CANHUANG</au><au>JI XIAOMING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Purification method of follicle stimulating hormone</title><date>2012-01-04</date><risdate>2012</risdate><abstract>The invention provides a purification method for preparing follicle-stimulating hormone FSH. 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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Purification method of follicle stimulating hormone |
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