Purification method of follicle stimulating hormone

The invention provides a purification method for preparing follicle-stimulating hormone FSH. The method comprises the steps as follows: (A) a raw material containing the FSH is contacted with an antibody, wherein, the raw material contains luteinizing hormone LH and/or chorionic gonadotropin CG as i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YAN HUIMIN, JI BIN, JIN CANHUANG, JI XIAOMING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides a purification method for preparing follicle-stimulating hormone FSH. The method comprises the steps as follows: (A) a raw material containing the FSH is contacted with an antibody, wherein, the raw material contains luteinizing hormone LH and/or chorionic gonadotropin CG as impurities, and the antibody is an antibody which specifically combines the LH and/or the CG but not crossly react with the FSH basically, thereby making the antibody form an antigen-antibody compound with the LH and/or the CG; (B) the formed antigen-antibody compound is removed from the raw material, thereby obtaining purified FSH. The invention also provides a method for preparing a drug composition containing the FSH.