Use of Diaminopyrimidine as P2X3 and P2x2/3 modulators in preparing medicine for treating respiratory diseases

The present invention relates to a method for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist. The method comprises: administering to a subject in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable...

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Bibliographische Detailangaben
Hauptverfasser:	CARTER DAVID S, BROKA CHRIS A, JAHANGIR ALAM, PARISH DANIEL W, MOORE AMY G, DILLON MICHAEL P, HAWLEY RONALD C, FORD ANTHONY P
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a method for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist. The method comprises: administering to a subject in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R , R , R , R , R , R , R and R are as defined herein.