Epitope capable of exciting human body anti-mycobacterium tuberculosis protective immunity reaction and use thereof

The invention relates to the field of molecular immunology. In recent years, tuberculosis begins to resume throughout the world and antibiotic treatment often fails because of the appearance of drug-resistant strain; the tuberculosis vaccines, namely, bacillus calmette-guerin vaccines, which are commonly used, are also limited. The purpose of the invention is to screen out the antigen epitope molecular simulating peptide which can stimulate the protective immune reaction of anti-mycobacterium tuberculosis in human bodies, study the protective immune reaction mechanism and further develop novel concatenated polyepitope tuberculosis vaccines. The invention provides an antigen epitope molecular simulating peptide which can stimulate the protective immune reaction of anti-mycobacterium tuberculosis in human bodies, the amino acid sequence of the peptide is shown in SEQ ID NO: 10. The invention also provides a screening method and usage of the peptide. The invention prevents and controls the occurrence and develop