Method for improving hyaluronic acid volume of production of fermentation production by adding oxygen carrier dodecane

A method for increasing the fermentation production of hyaluronic acid by adding an oxygen carrier of dodecane belongs to the technology field of applying the oxygen carrier to the optimization of the fermentation process. The invention adopts the method of adding the oxygen carrier of dedecane (1-5%, v/v) in a certain concentration to a fermentation broth after 8 hours' fermentation, so as to increase the dissolved oxygen concentration, thereby increasing the production of the hyaluronic acid. When the concentration of the dedecane is 5%, the production of the hyaluronic acid increases from 5.0g/L to 6.0g/L by contrast (no oxygen carrier is added). The method is simple, effective and applicable to the industrial production of the hyaluronic acid and has certain significance in guiding the optimization of other high-viscosity fermentation processes.