Rutin osmotic pump preparations and preparation thereof

The invention relates to a rutin osmotic pump preparation and the preparation method, which is produced through adding core tablet of the rutin osmotic pump into outer coating material to get the preparation, wherein, weight proportion for core tablet of the osmotic pump is as below: rutin 35, osmot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIAO CHANGJUN, ZANG ZHIHE, ZHANG ZHONGLIN, WU MIN, ZHONG LING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a rutin osmotic pump preparation and the preparation method, which is produced through adding core tablet of the rutin osmotic pump into outer coating material to get the preparation, wherein, weight proportion for core tablet of the osmotic pump is as below: rutin 35, osmotic substance 140 to 175, blocker 10.5 to 21, suspending agent 24.5 to 38.5 and lubricant 7 to 14. The invention is characterized in that: the preparation process is simple; the preparation method adopts ordinary table method, mainly showing that monolithic osmotic pump tablet technology is used forpreparing insoluble drug osmotic pump tablet; table core pressing adopts ordinary method without needing ensure perforation surface; drug release is more complete and can reach more than 85%, therebylowering administration frequency and improving compliance for convenient use of drugs for patients. The rutin osmotic pump preparation is especially suitable for patients with chronic diseases for long-term prescription.