Method for preparing valid target in gavel fruit vine fruit and application of the same

The invention relates to a preparation method of the effective parts of the fruit of the plant Capparis Spinosa, comprising the steps as follows: grinding the Capparis Spinosa fruit; extracting and decompressing with methanol or ethanol to get a crude extract; suspending the crude extract; degreasing with small molecular alkyl, then getting effective extract by extracting with butanol or eluting aqueous phase with water-alcohol system using macroporous resin column. The invention extracted from the effective part of Capparis Spinosa fruit is characterized in restraining proliferation of the fiber cell of the systemic sclerosis patients, expression of type I collagen and mRNA of the connective tissue growth factor, synthesis of protein, having no effect on proliferation of the fiber cell of the normal people, synthesis of collagen and expression of CTGF, being used in preparation of medicine for curing progressive systemic sclerosis, and facilitating a plurality of preparation comprising external use preparati