Meclofenoxate hydrochloride stomach-floating sustained release capsule and preparing method thereof

The invention discloses a meclofenoxate hydrochloride intra-gastric floating sustained release capsule. The invention adopts the intra-gastric floating sustained release technique to prevent the bad effect to the stability of the medicine in capsules caused by the elevation of the PH value in gastro...

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Bibliographische Detailangaben
Hauptverfasser: HU HAIYANG, CHEN DAWEI, MAO GUANXING
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a meclofenoxate hydrochloride intra-gastric floating sustained release capsule. The invention adopts the intra-gastric floating sustained release technique to prevent the bad effect to the stability of the medicine in capsules caused by the elevation of the PH value in gastrointestinal tract, avoid intestinal juice in human body from retrograding the meclofenoxate hydrochloride in capsules, which ensures that the medicine can release steadily, slowly and completely. The capsule of the invention should be taken twice every day and can float continuously in stomach for more than 8 hours; the medicine can be released for 12 hours continuously and the release rate at last reaches to over 90 percent, thereby enhancing the stability of the medicine, prolonging the curingeffect, greatly being convenient for patients to take medicine. The invention also provides the preparation method.