Method for rapidly measuring mizoribine drug concentration

The invention relates to an analysis measurement method of internal drug, in particular to a method for quickly measuring mizonbine density of human blood plasma, which comprises adding sample into an interior label, after protein deposition pretreatment, isocratically eluting under water-type flow phase condition, separating via a chromatographic column, and detecting via an ultrasonic detector. The invention has low sample consumption, simple, quick and sensitive pretreatment, which not demands expensive device and organic solvent, with wide application, low environment pollution, low cost and the application for detecting clinical general blood drug density.