Polyglutamate-medicament coupling compound with amino acid as communicating terminal

The invention aims at providing a poly-glutamic acid-drug conjugate which takes amino acids as connectors and the non-toxic pharmaceutically acceptable salts, wherein, the drugs are gemcitabine, paclitaxel or docetaxel. The Alpha-carboxyl of the amino acid molecules are connected with 5'-hydrox...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	ZHANG ZHENQING, ZHANG JIANXIN, ZHONG BOHUA, SHI WEIGUO, XIE JIANWEI, CHEN LANFU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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