Bracket for controlling releasing and elution of tranilast medicament coating
The invention relates to a tranilast medicine coat controlled release eluting bracket, pertaining to the field of medicine and medical appliance. The invention takes tranilast as the active component;three layers of a medicine loading layer, a controlled release layer and a protecting film layer are...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a tranilast medicine coat controlled release eluting bracket, pertaining to the field of medicine and medical appliance. The invention takes tranilast as the active component;three layers of a medicine loading layer, a controlled release layer and a protecting film layer are at the surface of the bracket. The bracket coat is evenly distributed on the surface of the bracket without crack and exfoliating phenomena; the original morphological structure can be kept after expanding. Proved by animal experiment result, the invention can effectively restrain the coronary hyperplasia and restenosis and markedly reduce the function of restraining the blood vessel endothelial cell at the same time; compared with the single coat or double coat structure of the existing drug-eluting bracket, the bracket of the invention can prevent the restenosis of the bracket, and has the functions of prventing bracket thrombus from being formed and promoting the early reparation of thebracket endothelium. |
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