Phosphine isocoumarin salt and preparation method thereof

The present invention relates to a new phosphonic isocoumarin salt and a preparation method. The compound of the present invention has a molecular formula shown on the right, wherein, R = alkyl of R = H, C1-10, naphthenic base of C3-7, aryl, the substituted derivatives; Z = Li, Na, K, Rb, Cs; Y = H, alkyl of C1-4, alkoxyl, carbonyl, halogen, CN, CF3, NO2, OH, amidocyanogen, aryl; X = H, C1, Br, I, alkyl of C1-10, naphthenic base of C3-7, aryl, the substituted derivatives. The phosphonic isocoumarin salt is prepared by the reaction of phosphonic isocoumarin ester under the function of alkali metal salt. The phosphonic isocoumarin salt of the present invention has certain water solubility and can be applied to the related fields of enzyme inhibitors, anti-rumor, etc.