Method for preparing human insulin inhaled dry powder using with supercritical fluid technology

A method of preparing an absorptive dry powder of human insulin by the supercritical liquid technology is a concrete method that the raw material of the human insulin is diluted into liquid medicine by acidic solution; the liquid medicine, counter solvent and supercritical carbon dioxide are synchronously pumped into a nozzle of a particle forming kettle for being mixed and atomized to form particles with the granularity of one to ten microns, and the particles are applied as the dry powder preparation for the pulmonary absorption. The absorptive dry powder of human insulin which is prepared by the invention can be used for preparing amorphous superfine powder, the drug loading quantity of which is more than 90 percent, according to different prescription designs, and the residual solventis very little; the water content is less than 10 percent; the amorphous superfine powder can be stably stored at the room temperature; the biological activity is hardly lost.