Process for preparation of high-purity meloxicam and meloxicam potassium salt

The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently tre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MESTERHAZY NORBERT, PECSI EVA, VOLK BALAZS, PORCS-MAKKAY MARTA, MEZEI TIBOR, HOFMANNE FEKETE VALERIA, NAGY KALMAN, KOERTVELYESSY GYULANE, KRASZNAI GYOERGY, LUKACS GYULA, SIMIG GYULA, VERECZKEYNE DONATH GYOERGYI, MOLNAR ENIKO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam.