Methods for refolding of recombinant antibodies

The present invention is generally directed to methods of producing an increase in the enrichment or recovery of preferred forms of IgG proteins. More particularly, the invention relates to subjecting preparations of such recombinant IgG proteins with a reduction/oxidation coupling reagent and optio...

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Bibliographische Detailangaben
1. Verfasser: DILLON THOMAS,REHDER DOUGLAS,BONDARENKO PAVEL,RICCI MARGARET,GADGIL HIMANSHU S.,BANKS DOUGLAS,ZHOU JOE,LU YUEFENG
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is generally directed to methods of producing an increase in the enrichment or recovery of preferred forms of IgG proteins. More particularly, the invention relates to subjecting preparations of such recombinant IgG proteins with a reduction/oxidation coupling reagent and optionally a chaotropic agent.