Substituted bicyclic imidazo-3-ylamine compounds

A method for diagnosing obstructive sleep apnea in a patient comprises identifying at least one protein biomarker for obstructive sleep apnea; obtaining a sample from the patient; and testing the sample for presence of the at least one protein biomarker. The protein biomarkers may include alpha-1 B-...

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1. Verfasser: KUEHNERT SVEIN,OBERBORSCH STEFAN,SUNDERMANN CORINNA,HAURAND MICHAEL,JOSTOCK RUTH,SCHIENE KLAUS,TZSCHENTKE THOMAS,CHRISTOPH THOMAS,KAULARTZ DAGMAR,ZEMOLKA S
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Sprache:eng
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Zusammenfassung:A method for diagnosing obstructive sleep apnea in a patient comprises identifying at least one protein biomarker for obstructive sleep apnea; obtaining a sample from the patient; and testing the sample for presence of the at least one protein biomarker. The protein biomarkers may include alpha-1 B-glycoprotein; kallikrein, laminin, aldosterone-binding protein and/or urocortin-2 precursor. The presence of the protein biomarkers may be detected using antibodies. These antibodies may be provided in an array for detecting the presence of the at least one protein biomarker or a pattern of protein biomarkers.