Long acting injectable crystal formulations of estradiol metabolites and methods of using same

The present invention provides sustained release formulations of estradiol metabolites whereby the in vivo pharmacokinetics are manipulated by a method selected from the group consisting of chemical modification, crystal packing formation, particle size or a combination thereof. Such compositions ar...

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Bibliographische Detailangaben
1. Verfasser: ALLISON S. DEAN
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides sustained release formulations of estradiol metabolites whereby the in vivo pharmacokinetics are manipulated by a method selected from the group consisting of chemical modification, crystal packing formation, particle size or a combination thereof. Such compositions are useful in the long-term treatment of a wide variety of diseases.