Pyrazolo[1,5-a]pyrimidine derivatives

Pyrazolo[1,5-a]pyrimidine derivatives

Pyrazolo[1,5-a]pyrimidine derivatives of the formula (I) and pharmaceutically acceptable salts thereof exhibit excellent MAPKAP-K2 inhibiting activity. Consequently, pharmaceutical products comprising these as active ingredients are expected to be effective in the prevention or treatment of MAPKAP-K...

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Bibliographische Detailangaben
1. Verfasser: KOSUGI TOMOMI,IMAI MINORU,MAKINO HIROAKI,TAKAKUWAMIKA,UNOKI GEN,KATAOKA KENICHIRO,MITCHELL DALE R.,SIMPSON DONALD J.,HARRIS CLIFFORD J.,LE JOELLE,YAMAKOSHI YUKO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Pyrazolo[1,5-a]pyrimidine derivatives of the formula (I) and pharmaceutically acceptable salts thereof exhibit excellent MAPKAP-K2 inhibiting activity. Consequently, pharmaceutical products comprising these as active ingredients are expected to be effective in the prevention or treatment of MAPKAP-K2 mediated diseases, for example, inflammatory diseases, autoimmune diseases, osteoclastic disorder, cancer and/or tumor growth.