Lrp4/Corin dopamine-producing neuron precursor cell marker

A polynucleotide probe and antibody for detecting an Lrp4/Corin dopamine-producing neuron precursor cell marker by which dopamine-producing neuron precursor cells can be efficiently separated; and a method of selecting precursor cells by using the same. By using the expression of the Lrp4 in cells,...

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Bibliographische Detailangaben
1. Verfasser:	SAKAMOTO YOSHIMASA,ONO YUICHI,IMAI TOSHIO,NAKAGAWA YASUKO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A polynucleotide probe and antibody for detecting an Lrp4/Corin dopamine-producing neuron precursor cell marker by which dopamine-producing neuron precursor cells can be efficiently separated; and a method of selecting precursor cells by using the same. By using the expression of the Lrp4 in cells, cells suitable for the transplantation therapy for neurodegenerative diseases including Parkinson'sdisease can be selected while taking safety, survival ratio and network formation ability into consideration.