PROCESS FOR PREPARATION OF 4-ALKOXY-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES
本发明涉及式Ⅰ的４－烷氧基－吡啶并［２，３－ｄ］嘧啶－衍生物及其药理学上可接受的盐之制备方法。式中Ｒ1，Ｒ2，Ｒ3和Ｒ4正如在说明书中已定义了的。所含式Ⅰ的化合物具有解除脉管痉挛的作用，它们对脑、心脏和末稍脉管病，均有疗效。本发明还涉及的４－烷氧基－吡啶并－［２，３－ｄ］嘧啶－衍生物在治疗脉管病上的应用以及它们在药剂中的使用。 4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmoly...
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| creator | GRHARD SATZINGER JURGEN KLEINSCHROTH KARL MANNHARDT ET AL |
| description | 本发明涉及式Ⅰ的４－烷氧基－吡啶并［２，３－ｄ］嘧啶－衍生物及其药理学上可接受的盐之制备方法。式中Ｒ1，Ｒ2，Ｒ3和Ｒ4正如在说明书中已定义了的。所含式Ⅰ的化合物具有解除脉管痉挛的作用，它们对脑、心脏和末稍脉管病，均有疗效。本发明还涉及的４－烷氧基－吡啶并－［２，３－ｄ］嘧啶－衍生物在治疗脉管病上的应用以及它们在药剂中的使用。
4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arterioschlerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality. |
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4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arterioschlerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality.</description><edition>4</edition><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1989</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890524&DB=EPODOC&CC=CN&NR=1004274B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890524&DB=EPODOC&CC=CN&NR=1004274B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GRHARD SATZINGER</creatorcontrib><creatorcontrib>JURGEN KLEINSCHROTH</creatorcontrib><creatorcontrib>KARL MANNHARDT</creatorcontrib><creatorcontrib>ET AL</creatorcontrib><title>PROCESS FOR PREPARATION OF 4-ALKOXY-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES</title><description>本发明涉及式Ⅰ的４－烷氧基－吡啶并［２，３－ｄ］嘧啶－衍生物及其药理学上可接受的盐之制备方法。式中Ｒ1，Ｒ2，Ｒ3和Ｒ4正如在说明书中已定义了的。所含式Ⅰ的化合物具有解除脉管痉挛的作用，它们对脑、心脏和末稍脉管病，均有疗效。本发明还涉及的４－烷氧基－吡啶并－［２，３－ｄ］嘧啶－衍生物在治疗脉管病上的应用以及它们在药剂中的使用。
4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arterioschlerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1989</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAMCPJ3dg0OVnDzD1IICHINcAxyDPH091Pwd1Mw0XX08faPiNQNiAzydPFX0DDSMdZ10VQAcX09XTz9XBVcXIM8w4AawlyDeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvLOfoYGBiZG5iZOTMRFKALFhLGg</recordid><startdate>19890524</startdate><enddate>19890524</enddate><creator>GRHARD SATZINGER</creator><creator>JURGEN KLEINSCHROTH</creator><creator>KARL MANNHARDT</creator><creator>ET AL</creator><scope>EVB</scope></search><sort><creationdate>19890524</creationdate><title>PROCESS FOR PREPARATION OF 4-ALKOXY-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES</title><author>GRHARD SATZINGER ; JURGEN KLEINSCHROTH ; KARL MANNHARDT ; ET AL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN1004274BB3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>1989</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GRHARD SATZINGER</creatorcontrib><creatorcontrib>JURGEN KLEINSCHROTH</creatorcontrib><creatorcontrib>KARL MANNHARDT</creatorcontrib><creatorcontrib>ET AL</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GRHARD SATZINGER</au><au>JURGEN KLEINSCHROTH</au><au>KARL MANNHARDT</au><au>ET AL</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARATION OF 4-ALKOXY-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES</title><date>1989-05-24</date><risdate>1989</risdate><abstract>本发明涉及式Ⅰ的４－烷氧基－吡啶并［２，３－ｄ］嘧啶－衍生物及其药理学上可接受的盐之制备方法。式中Ｒ1，Ｒ2，Ｒ3和Ｒ4正如在说明书中已定义了的。所含式Ⅰ的化合物具有解除脉管痉挛的作用，它们对脑、心脏和末稍脉管病，均有疗效。本发明还涉及的４－烷氧基－吡啶并－［２，３－ｄ］嘧啶－衍生物在治疗脉管病上的应用以及它们在药剂中的使用。
4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arterioschlerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PREPARATION OF 4-ALKOXY-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES |
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