PROCESS FOR PREPARATION OF 4-ALKOXY-PYRIDO (2,3-D) PYRIMIDINE DERIVATIVES
本发明涉及式Ⅰ的4-烷氧基-吡啶并[2,3-d]嘧啶-衍生物及其药理学上可接受的盐之制备方法。式中R1,R2,R3和R4正如在说明书中已定义了的。所含式Ⅰ的化合物具有解除脉管痉挛的作用,它们对脑、心脏和末稍脉管病,均有疗效。本发明还涉及的4-烷氧基-吡啶并-[2,3-d]嘧啶-衍生物在治疗脉管病上的应用以及它们在药剂中的使用。 4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmoly...
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Zusammenfassung: | 本发明涉及式Ⅰ的4-烷氧基-吡啶并[2,3-d]嘧啶-衍生物及其药理学上可接受的盐之制备方法。式中R1,R2,R3和R4正如在说明书中已定义了的。所含式Ⅰ的化合物具有解除脉管痉挛的作用,它们对脑、心脏和末稍脉管病,均有疗效。本发明还涉及的4-烷氧基-吡啶并-[2,3-d]嘧啶-衍生物在治疗脉管病上的应用以及它们在药剂中的使用。
4-Alkoxy-pyrido[2,3-d]pyrimidine derivatives are described as well as processes for their preparation. For reason of their vasospasmolytic effects these compounds are mainly indicated for the treatment of cerebral, cardiac, and peripheral vascular diseases such as myocardiac ischemia, cerebral infarction, pulmonary thromboses, as well as in cases of arterioschlerosis and other stenotic disorders. They are therefore valuable agents for combating cardiovascular mortality. |
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