Amine derivative

Amine derivative

The invention relates to (1S)-1-isobutoxymethyl-3-methylbutylamine useful as an intermediate in the synthesis of sodium (2S,3S)-3-ÄÄ(1S)-1-isobutoxymethyl-3-methylbutylÜcarbamoylÜoxirane-2-carboxylate and a process for production thereof. The process comprises reacting L-leucinol with a compound rep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: TENDO ATSUSHI,TAKAHASHI TOSHIHIRO,YAMAKAWA TOMIO
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to (1S)-1-isobutoxymethyl-3-methylbutylamine useful as an intermediate in the synthesis of sodium (2S,3S)-3-ÄÄ(1S)-1-isobutoxymethyl-3-methylbutylÜcarbamoylÜoxirane-2-carboxylate and a process for production thereof. The process comprises reacting L-leucinol with a compound represented by the following formula in the presence of a base and reducing the obtained (1S)-1-(2-methyl-2-propenoxymethyl)-3-methylbutylamine: Äin which X is a leaving groupÜ.