Hidrogeles de colágeno útiles como vehículos celulares

Hidrogeles de colágeno útiles como vehículos celulares A collagen hydrogel which has a 3D fibrillar structure with micropores obtainable by a process including: providing an acidic mass of native Type I collagen fibers dispersed in water in a concentration comprised between 1-15% in weight; b) neutr...

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Hauptverfasser:	Jesús Maria IZCO ZARATIEGUI, Teresa ZÚÑIGA ARRARÁS, Amaia GUEMBE LAPUENTE, José Ignacio RECALDE IRURZUN
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	Hidrogeles de colágeno útiles como vehículos celulares A collagen hydrogel which has a 3D fibrillar structure with micropores obtainable by a process including: providing an acidic mass of native Type I collagen fibers dispersed in water in a concentration comprised between 1-15% in weight; b) neutralizing the acidic mass to adjust the pH to physiological pH; and c) applying beta radiation in a range of up to 50 KGy; wherein the acidic mass has a pH between 0.5-5; and fibers, wherein the acidic mass includes fibers, wherein at least 90% of the total mass of the fibers have a length in of 1 μm to 2500 μm and a fiber diameter of from 0.1 to 150 μm measured at a pH between 1 and 2. A process for its preparation as well as its use as support for cell tissue or as scaffold of cultured meat, as well as the hydrogel for use in biomedical applications.