Composición que comprende inhibidor de la alfa-1 proteinasa altamente concentrado y procedimiento para la obtención de la misma

Composición que comprende inhibidor de la alfa-1 proteinasa altamente concentrado y procedimiento para la obtención de la misma

Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concent...

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Bibliographische Detailangaben
Hauptverfasser: Kevin WEE, Charles MILLER, Anthony KLOS, Thomas P ZIMMERMAN, Kelly GLANCY, Michelle StPETER, Eric ALLGAIER, James REBBEOR
Format: Patent
Sprache:spa
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).