Inhibidores de azaquinazoline de proteína atípica kinase c

COMPUESTOS DERIVADOS DE pirido[3,4-d]pirimidina; COMPOSICION FARMACEUTICA QUE LOS COMPRENDE Y EL USO PARA TRATAR UN TRASTORNO O CONDICION DEPENDIENTE DE APKC TAL COMO UN TRASTORNO PROLIFERATIVO. The present application provides azaquinazoline compounds as defined herein. This application further des...

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Hauptverfasser: GREGORY R. OTT, ALLISON L. ZULLI, KATHERINE M. FOWLER, EUGEN F. MESAROS, CRAIG A. ZIFICSAK, IKEOLUWA OLOWAYE, ROBERT L. HUDKINS, NATHANIEL JT MONCK, CHRISTELLE N. SOUDY, HENRY J. BRESLIN, BRUCE D. DORSEY, JONATHAN R.A. ROFFEY, MING TAO, EMMA L. MORRIS, BENJAMIN J. DUGAN, GREGOIRE A PAVE
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creator GREGORY R. OTT
ALLISON L. ZULLI
KATHERINE M. FOWLER
EUGEN F. MESAROS
CRAIG A. ZIFICSAK
IKEOLUWA OLOWAYE
ROBERT L. HUDKINS
NATHANIEL JT MONCK
CHRISTELLE N. SOUDY
HENRY J. BRESLIN
BRUCE D. DORSEY
JONATHAN R.A. ROFFEY
MING TAO
EMMA L. MORRIS
BENJAMIN J. DUGAN
GREGOIRE A PAVE
description COMPUESTOS DERIVADOS DE pirido[3,4-d]pirimidina; COMPOSICION FARMACEUTICA QUE LOS COMPRENDE Y EL USO PARA TRATAR UN TRASTORNO O CONDICION DEPENDIENTE DE APKC TAL COMO UN TRASTORNO PROLIFERATIVO. The present application provides azaquinazoline compounds as defined herein. This application further describes compositions comprising the same. These azaquinazoline compounds and their salts have atypical protein kinase C ("aPKC") inhibitory activity, and may be used to treat proliferative disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Inhibidores de azaquinazoline de proteína atípica kinase c
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