Composicion que comprende n-(4-{4-amino-7-[1-(2-hidroxietil)-1h-pirazol-4-il]tieno[3,2-c]priridin-3-il}fenil)-n'-(3-fluorofenil)urea o una sal, b) polietilenglicol, c) aceite de ricino polioxietilado y d) etanol; y su uso para tratar el cancer

Composicion que comprende n-(4-{4-amino-7-[1-(2-hidroxietil)-1h-pirazol-4-il]tieno[3,2-c]priridin-3-il}fenil)-n'-(3-fluorofenil)urea o una sal, b) polietilenglicol, c) aceite de ricino polioxietilado y d) etanol; y su uso para tratar el cancer

A composition comprises a kinase inhibitory compound, e.g., N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N′-(3-fluorophenyl)urea, in a mixture comprising (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable s...

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Bibliographische Detailangaben
Hauptverfasser: DIAS LLOYD E, PADDEN BRIAN E, LIPARI JOHN M, SPENCE JULIE K, SHI YI
Format: Patent
Sprache:spa
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A composition comprises a kinase inhibitory compound, e.g., N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N′-(3-fluorophenyl)urea, in a mixture comprising (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable surfactant. The composition is suitable for dilution with an IV solution for administration to a subject in need thereof for treatment of a cancer.