ANTICUERPOS ANTI-FACTOR D; ACIDOS NUCLEICOS QUE LOS CODIFICAN; VECTOR Y LINEA CELULAR QUE LOS COMPRENDEN; METODO DE PRODUCCION; COMPOSICION FARMACEUTICA QUE COMPRENDE A LOS ANTICUERPOS; Y SU USO PARA TRATAR TRASTORNOS MEDIADOS POR EL COMPLEMENTO COMO

The invention relates to anti-Factor D antibodies and Factor D-binding fragments thereof, their nucleic acid sequences, the host cells and vectors that harbor these antibodies and Factor D-binding fragments, the method of making anti-Factor D antibodies and Factor D-binding fragments thereof, and th...

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Bibliographische Detailangaben
Hauptverfasser: WU, HERREN, SINGH, SANJAYA, FUNG, SEK CHUNG, LOWMAN, HENRY B., KELLEY, ROBERT F., AN, LING-L
Format: Patent
Sprache:spa
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Zusammenfassung:The invention relates to anti-Factor D antibodies and Factor D-binding fragments thereof, their nucleic acid sequences, the host cells and vectors that harbor these antibodies and Factor D-binding fragments, the method of making anti-Factor D antibodies and Factor D-binding fragments thereof, and the method of detecting Factor D. The invention also relates to compositions comprising the anti-Factor D antibodies or the Factor D-binding fragments thereof, their use in preparation of medicaments and treating disorders associated with excessive or uncontrolled complement activation.