COMPUESTOS DERIVADOS DE 2-FENIL-3,4-DIHIDRO-1H-ISOQUINOLINA, MODULADORES DE CANALES DE POTASIO; COMPUESTO INTERMEDIARIO; COMPOSICION FARMACEUTICA; Y USO PARA PREVENIR O TRATAR UN TRASTORNO PROVOCADO POR HIPEREXCITABILIDAD DEL SISTEMA NERVIOSO, TAL CO

COMPUESTOS DERIVADOS DE 2-FENIL-3,4-DIHIDRO-1H-ISOQUINOLINA, MODULADORES DE CANALES DE POTASIO; COMPUESTO INTERMEDIARIO; COMPOSICION FARMACEUTICA; Y USO PARA PREVENIR O TRATAR UN TRASTORNO PROVOCADO POR HIPEREXCITABILIDAD DEL SISTEMA NERVIOSO, TAL CO

This invention provides a compound of formula IA where X O or S; Y is O or S; q=1 or 0; and other substituents are defined herein. Such compounds can affect the opening of, or otherwise modulate, voltage-gated potassium channels. They are potentially useful for the treatment and prevention of diseas...

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Bibliographische Detailangaben
Hauptverfasser: JEAN-MICHEL VERNIER, JIM ZHEN WU, MARTHA ALICIA DE LA ROSA, GARY LEE LARSON, HUANMING CHEN, IAN WAYNE CHENEY
Format: Patent
Sprache:spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:This invention provides a compound of formula IA where X O or S; Y is O or S; q=1 or 0; and other substituents are defined herein. Such compounds can affect the opening of, or otherwise modulate, voltage-gated potassium channels. They are potentially useful for the treatment and prevention of diseases and disorders which are affected by activation or modulation of potassium ion channels. One such condition is seizure disorders.