COMPUESTOS DERIVADOS DE AZABENZOTIOFENIL; COMPOSICION FARMACEUTICA; Y USO PARA LA INHIBICION DEL CRECIMIENTO CELULAR ANOMALO O DE TRATAMIENTO DE UN TRASTORNO HIPERPROLIFERATIVO
The invention relates to azabenzothiophenyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to azabenzothiophenyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or...
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| creator | PRICE, STEPHEN WILLIAMS, KAREN SAVY, PASCAL PIERRE DYKE, HAZEL JOAN MONTANA, JOHN GARY STANLEY, MARK S. BAO, LIANG |
| description | The invention relates to azabenzothiophenyl compounds of Formula I with anti-cancer and/or anti-inflammatory activity and more specifically to azabenzothiophenyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPUESTOS DERIVADOS DE AZABENZOTIOFENIL; COMPOSICION FARMACEUTICA; Y USO PARA LA INHIBICION DEL CRECIMIENTO CELULAR ANOMALO O DE TRATAMIENTO DE UN TRASTORNO HIPERPROLIFERATIVO |
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