COMPOSICION INMUNOGENICA MENINGOCOCICA MULTIVALENTE, DE VESICULAS DE MEMBRANA EXTERNA, QUE COMPRENDE UNA VESICULA CON ACTIVIDAD HOMOLOGA DE UN SUBSEROTIPO PREVALENTE EN UN PAIS Y OTRA VESICULA CON ACTIVIDAD HETEROLOGA, QUE TIENE DISMINUIDA UNA PROTEI

COMPOSICION INMUNOGENICA MENINGOCOCICA MULTIVALENTE, DE VESICULAS DE MEMBRANA EXTERNA, QUE COMPRENDE UNA VESICULA CON ACTIVIDAD HOMOLOGA DE UN SUBSEROTIPO PREVALENTE EN UN PAIS Y OTRA VESICULA CON ACTIVIDAD HETEROLOGA, QUE TIENE DISMINUIDA UNA PROTEI

The present invention relates to vaccine compositions for the effective prevention of neisserial, preferably meningococcal, disease. The vaccine of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived...

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Bibliographische Detailangaben
1. Verfasser: BARBERA MORALES, DOMINGUEZ ALVAREZ FRANCISCO, DESMONS PIERREY POOLMAN JAN
Format: Patent
Sprache:spa
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to vaccine compositions for the effective prevention of neisserial, preferably meningococcal, disease. The vaccine of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived from a meningococcal strain with a serosubtype that is prevalent in a country of use, and at least one bleb with heterologous bacterial activity which is derived from a meningococcal strain which need not have a serosubtype that is prevalent in the country of use.