GLYKOPEPTIDE UND VERFAHREN ZU IHRER HERSTELLUNG

Glycopeptides according to the present invention have the formula: (I) wherein n=1 or 2; R is a residue of an aminoacid or linear peptides built of 2 to 5 amino acid residues. These compounds are prepared by the method involving condensation of unblocked muramyl-containing N-acetylamino-sugars of th...

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Hauptverfasser: JURY ANATOLIEVICH OVCHINNIKOV, TATYANA MIKHAILOVNA ANDRONOVA, VERONIKA PETROVNA MALKOVA, LARISA IVANOVNA ROSTOVTSEVA, IRINA BORISOVNA SOROKINA, VADIM TIKHONOVICH IVANOV
Format: Patent
Sprache:ger
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Zusammenfassung:Glycopeptides according to the present invention have the formula: (I) wherein n=1 or 2; R is a residue of an aminoacid or linear peptides built of 2 to 5 amino acid residues. These compounds are prepared by the method involving condensation of unblocked muramyl-containing N-acetylamino-sugars of the formula: (II) wherein n=1 or 2, with blocked aminoacids or peptides. The method of this invention makes it possible to produce synthetic glycopeptides manifesting a biological activity. These compounds possess an antitumor and adjuvant activity.