Therapeutically active 6-(alpha-hydroxyethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, and processes for their preparation

The therapeutically active compounds of the formula III, in which the dotted line indicates the unsaturated or saturated 2,3 bond and R' and X have the meaning given in Claim 1, as well as their pharmaceutically acceptable salts and esters, are valuable antibiotics. They can be obtained by hydr...

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Hauptverfasser: DAVID HOUNG-MIN SHIH, BURTON GRANT CHRISTENSEN
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creator DAVID HOUNG-MIN SHIH
BURTON GRANT CHRISTENSEN
description The therapeutically active compounds of the formula III, in which the dotted line indicates the unsaturated or saturated 2,3 bond and R' and X have the meaning given in Claim 1, as well as their pharmaceutically acceptable salts and esters, are valuable antibiotics. They can be obtained by hydrogenating cleavage and, where appropriate, by hydrogenating the double bond of thienamycin of the formula IV and its derivatives.
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They can be obtained by hydrogenating cleavage and, where appropriate, by hydrogenating the double bond of thienamycin of the formula IV and its derivatives.</description><language>eng ; ger</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1983</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19830930&amp;DB=EPODOC&amp;CC=CH&amp;NR=638522A5$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19830930&amp;DB=EPODOC&amp;CC=CH&amp;NR=638522A5$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DAVID HOUNG-MIN SHIH</creatorcontrib><creatorcontrib>BURTON GRANT CHRISTENSEN</creatorcontrib><title>Therapeutically active 6-(alpha-hydroxyethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, and processes for their preparation</title><description>The therapeutically active compounds of the formula III, in which the dotted line indicates the unsaturated or saturated 2,3 bond and R' and X have the meaning given in Claim 1, as well as their pharmaceutically acceptable salts and esters, are valuable antibiotics. 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They can be obtained by hydrogenating cleavage and, where appropriate, by hydrogenating the double bond of thienamycin of the formula IV and its derivatives.</abstract><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Therapeutically active 6-(alpha-hydroxyethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives, and processes for their preparation
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