PROSTACYCLINANALOGA
This invention relates to certain structural and pharmacological analogs of 5,6-dihydroprostacyclin (PGI1) wherein an endocyclic double bond is present at the C-6 to C-7 position. These novel unsaturated prostacyclin-type compounds are useful for the pharmacological purposes for which prostacyclin i...
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Zusammenfassung: | This invention relates to certain structural and pharmacological analogs of 5,6-dihydroprostacyclin (PGI1) wherein an endocyclic double bond is present at the C-6 to C-7 position. These novel unsaturated prostacyclin-type compounds are useful for the pharmacological purposes for which prostacyclin is used, e.g., as antithrombotic agents, smooth muscle stimulators, gastric antisecretory agents, antihypertensive agents, antiasthma agents, nasal decongestants, or regulators of fertility and procreation. |
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