VERFAHREN ZUR HERSTELLUNG VON CEPHALOSPORINVERBINDUNGEN

Antibiotic compounds of the general formula (I) [wherein R is a phenyl, thienyl or furyl group; Ra and Rb, which may be the same or different, are each selected from hydrogen, C1-4 alkyl, C2-4 alkenyl C3-7 cycloalkyl, phenyl, naphthyl, thienyl, furyl, carboxy, C2-5 alkoxycarbonyl and cyano, or Ra and Rb together with the carbon atom to which they are attached from a C3-7 cycloalkylidene or cycloalkenylidene group; Rc is hydrogen or lower alkyl; Rd is hydroxy, lower alkoxy, aralkoxy or aryloxy; m and n are each 0 or 1 such that the sum of m and n is 0 or 1; and P is selected from a hydrogen atom, a halogen atom and various organic groups] and non-toxic derivatives thereof.