Process for preparing novel N-2-(2-furylethyl)amines, their salts and optical antipodes

Process for preparing novel N-2-(2-furylethyl)amines, their salts and optical antipodes

The novel N-2-(2-furylethyl)amines of the formula I, in which the symbols R , R and R have the meaning given in Claim 1, have an inhibitory effect on the monoamine oxidases without any undesirable amphetamine effect. They are prepared by reacting a compound of the formula II, in which A denotes carb...

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Bibliographische Detailangaben
Hauptverfasser: JUDIT HERMANN-VOEROES, ZOLTAN ECSERY, ZOLTAN TOEROEK, EVA SOMFAI, GABOR BERNATH, JOZSEF KNOLL
Format: Patent
Sprache:eng ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The novel N-2-(2-furylethyl)amines of the formula I, in which the symbols R , R and R have the meaning given in Claim 1, have an inhibitory effect on the monoamine oxidases without any undesirable amphetamine effect. They are prepared by reacting a compound of the formula II, in which A denotes carbonyl, with a compound of the formula III and reducing the resulting Schiff's base.