VERFAHREN ZUR HERSTELLUNG VON NEUEN ESTERN DES N-ACYLIERTEN THIENAMYCINS

Disclosed are N-acyl and carboxyl derivatives of the antibiotic thienamycin, which has the following structure: Such derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives and methods of tre...

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Bibliographische Detailangaben
Hauptverfasser:	DAVID HOUNG-MIN SHIH, JOHN HANNAH, BURTON GRANT CHRISTENSEN, WILLIAM JOSEPH LEANZA
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are N-acyl and carboxyl derivatives of the antibiotic thienamycin, which has the following structure: Such derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives and methods of treatment comprising administering such derivatives and compositions when an antibiotic effect is indicated.