VERFAHREN ZUR HERSTELLUNG VON NEUEN 3-PHENOXY-2-HYDROXY-1-AMINOPROPANEN

New phenoxy-amino-propanols of formula wherein R1 is alkenyl, alkynyl, alkoxyalkyl or alkenyloxyalkyl with 2-6 C atoms in each case or cycloalkyl with 3-8 C atoms; and R2 is alkyl or hydroxyalkyl with 1-6 C atoms in each case, cycloalkyl with 3-8 C atoms, aralkyl or aralkyl wherein the aryl radical...

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Hauptverfasser: HANS-JOACHIM ENENKEL, KLAUS MINCK, HANS-JOCHEN SCHLIEP, ROCHUS JONAS, KARL-HEINZ BECKER
Format: Patent
Sprache:ger
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Zusammenfassung:New phenoxy-amino-propanols of formula wherein R1 is alkenyl, alkynyl, alkoxyalkyl or alkenyloxyalkyl with 2-6 C atoms in each case or cycloalkyl with 3-8 C atoms; and R2 is alkyl or hydroxyalkyl with 1-6 C atoms in each case, cycloalkyl with 3-8 C atoms, aralkyl or aralkyl wherein the aryl radical is mono- to tri-substituted by alkyl, alkoxy, OH, F and/or Cl or mono-substituted by methylenedioxy, with a total of 7-15 C atoms in each case, and the physiologically acceptable acid addition salts thereof, exhibit various pharmacological properties including isoprenaline-antagonism on the heart rate and blood pressure.