Process for the preparation of 1-methyl-2-(phenyloxymethyl)-5-nitroimidazoles

Novel 1-methyl-2-(phenyloxymethyl)-5-nitroimidazoles of the formula I are prepared by reaction of 1-methyl-2-(aminophenyloxymethyl)- 5-nitroimidazole with an appropriate carboxylic acid amide, carboxylic acid thioamide, lactam, thiolactam, acetal of a carboxylic acid amide or a lactam. The symbols i...

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Hauptverfasser: ERHARDT WINKELMANN, WOLFGANG RAETHER
Format: Patent
Sprache:eng
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Zusammenfassung:Novel 1-methyl-2-(phenyloxymethyl)-5-nitroimidazoles of the formula I are prepared by reaction of 1-methyl-2-(aminophenyloxymethyl)- 5-nitroimidazole with an appropriate carboxylic acid amide, carboxylic acid thioamide, lactam, thiolactam, acetal of a carboxylic acid amide or a lactam. The symbols in formula I have the meaning given in Claim 1. The compounds of the formula I and their physiologically tolerable salts are suitable for the control of protozoal disorders. They are also active against helminths and ectoparasites.