Process for the preparation of stable crystalline salts of cephalosporins

Process for the preparation of stable crystalline salts of cephalosporins

In order to obtain stable crystalline salts of formula a solution of cephalosporanic acid (formula I, X = H) is reacted with a solution of a compound XQ (X = Li or an ammonium residue and Q = anion of an acid HQ of pKa of 4 or more) and the salt obtained is crystallised. The compounds exhibit antiba...

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Bibliographische Detailangaben
Hauptverfasser: BRIAN PICTON SWANN, WILLIAM BOFFEY JAMIESON
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:In order to obtain stable crystalline salts of formula a solution of cephalosporanic acid (formula I, X = H) is reacted with a solution of a compound XQ (X = Li or an ammonium residue and Q = anion of an acid HQ of pKa of 4 or more) and the salt obtained is crystallised. The compounds exhibit antibacterial properties.