7-Cyanacetylaminocephalosporanic acid derivs
The cpds. are of formula (I): NC - CR1R2-CONH in which R1 and Ri are each H, an opt. substd. monovalent hydrocarbon radical or a heterocyclic ring linked through carbon, or R1 and R2 together form a divalent opt. substd. hydrocarbon radical which may contain heteroatoms in the carbon chain, and R3 i...
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Zusammenfassung: | The cpds. are of formula (I): NC - CR1R2-CONH in which R1 and Ri are each H, an opt. substd. monovalent hydrocarbon radical or a heterocyclic ring linked through carbon, or R1 and R2 together form a divalent opt. substd. hydrocarbon radical which may contain heteroatoms in the carbon chain, and R3 is an aromatic heterocyclic radical which is linked to the S atom by carbon, and which contains at least two N atoms and one additional heteroatom which may be N, O or S. I are active against gram positive and gram negative bacteria, e.g. S. aureus, E. coli, Llebsiella pneumoniae, Salmonella Thyphosa and Bacterium proteus. |
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