Cholesterol derivs

I Cpds. of general formula:- (I) where R' = Cl, OH, (1-18C) O-acyl or (1-4C)O-alkyl and R2 = one of the following:- 1. CH(Me)N(Me)CH2CHMe2 2. CH(Me)CH2N(Me)CHMe2 3. CH(Me)N(Me)(CH2)2CHMe2 4. CH(Me)CH2N(Me)CH2CHMe2 5. CH(Me)(CH2)2N(Me)CHMe2 6. CH(Me)(CH2)2NMe2 7. CH(Me)(CH2)2NEtMe 8. CH(Me)O(CH2...

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Hauptverfasser:	BORK,KARL-HEINZ,DR, KRAEMER,JOSEF,DR, WATZEL,RUDOLF,DR, BRUECKNER,KLAUS,DR, IRMSCHER,KLAUS,DR, VOEGE,HANS-OTTO,DR
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
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creator	BORK,KARL-HEINZ,DR KRAEMER,JOSEF,DR WATZEL,RUDOLF,DR BRUECKNER,KLAUS,DR IRMSCHER,KLAUS,DR VOEGE,HANS-OTTO,DR
description	I Cpds. of general formula:- (I) where R' = Cl, OH, (1-18C) O-acyl or (1-4C)O-alkyl and R2 = one of the following:- 1. CH(Me)N(Me)CH2CHMe2 2. CH(Me)CH2N(Me)CHMe2 3. CH(Me)N(Me)(CH2)2CHMe2 4. CH(Me)CH2N(Me)CH2CHMe2 5. CH(Me)(CH2)2N(Me)CHMe2 6. CH(Me)(CH2)2NMe2 7. CH(Me)(CH2)2NEtMe 8. CH(Me)O(CH2)2NMe2 9. O-(CH2)2NEt2 10. -O-(CH2)2 11. -N(Me)(CH2)2CHMe2 12. -N(Me)(CH2)2NHCHMe2 13. -N(Me)(CH2)2N(Et)CHMe2 14. CH(Me)N(Me)CH2CHEt2 15. CH(Me)N(Et)CH2CHEt2 16. CH(Me)CH2N(Me)CHEt2 17. CH(Me)CH2N(Et)CHEt2 18. -O-(CH2)2NMeEt 19. N(Me)(CH2)2CHMeEt 20. CH(Me)N(Et)CH2CHMe2 21. CH(Me)CH2N(Et)CHMe2 22. CH(Me)N(Et)(CH2)2CHMe2 23. CH(Me)CH2N(Et)CH2CHMe2 24. CH(Me)(CH2)2N(Et)CHMe2 25. CH(Me)(CH2)3NMe2 26. CH(Me)(CH2)2NEt2 27. -O-(CH2)2NMe2 28. -O-(CH2)2 29. -O-(CH2)3NMe2 30. -N(Me)(CH2)3CHMe2 31. -N(Me)(CH2)2N(Me)CHMe2 32. -N(Me)(CH2)2-O-CHMe2 33. CH(Me)N(Me)CH2CHMeEt 34. CH(Me)N(Et)CH2CHMeEt 35. CH(Me)CH2N(Me)CHMeEt 36. CH(Me)CH2N(Et)CHMeEt 37. N(Me)(CH2)2CHEt2 II Acid addn. salts and pharm. prepns. of I. Hypocholesteremics, blocking cholesterol synthesis. Dose 2-300 mg.
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CH(Me)N(Me)CH2CHMe2 2. CH(Me)CH2N(Me)CHMe2 3. CH(Me)N(Me)(CH2)2CHMe2 4. CH(Me)CH2N(Me)CH2CHMe2 5. CH(Me)(CH2)2N(Me)CHMe2 6. CH(Me)(CH2)2NMe2 7. CH(Me)(CH2)2NEtMe 8. CH(Me)O(CH2)2NMe2 9. O-(CH2)2NEt2 10. -O-(CH2)2 11. -N(Me)(CH2)2CHMe2 12. -N(Me)(CH2)2NHCHMe2 13. -N(Me)(CH2)2N(Et)CHMe2 14. CH(Me)N(Me)CH2CHEt2 15. CH(Me)N(Et)CH2CHEt2 16. CH(Me)CH2N(Me)CHEt2 17. CH(Me)CH2N(Et)CHEt2 18. -O-(CH2)2NMeEt 19. N(Me)(CH2)2CHMeEt 20. CH(Me)N(Et)CH2CHMe2 21. CH(Me)CH2N(Et)CHMe2 22. CH(Me)N(Et)(CH2)2CHMe2 23. CH(Me)CH2N(Et)CH2CHMe2 24. CH(Me)(CH2)2N(Et)CHMe2 25. CH(Me)(CH2)3NMe2 26. CH(Me)(CH2)2NEt2 27. -O-(CH2)2NMe2 28. -O-(CH2)2 29. -O-(CH2)3NMe2 30. -N(Me)(CH2)3CHMe2 31. -N(Me)(CH2)2N(Me)CHMe2 32. -N(Me)(CH2)2-O-CHMe2 33. CH(Me)N(Me)CH2CHMeEt 34. CH(Me)N(Et)CH2CHMeEt 35. CH(Me)CH2N(Me)CHMeEt 36. CH(Me)CH2N(Et)CHMeEt 37. N(Me)(CH2)2CHEt2 II Acid addn. salts and pharm. prepns. of I. Hypocholesteremics, blocking cholesterol synthesis. 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CH(Me)N(Me)CH2CHMe2 2. CH(Me)CH2N(Me)CHMe2 3. CH(Me)N(Me)(CH2)2CHMe2 4. CH(Me)CH2N(Me)CH2CHMe2 5. CH(Me)(CH2)2N(Me)CHMe2 6. CH(Me)(CH2)2NMe2 7. CH(Me)(CH2)2NEtMe 8. CH(Me)O(CH2)2NMe2 9. O-(CH2)2NEt2 10. -O-(CH2)2 11. -N(Me)(CH2)2CHMe2 12. -N(Me)(CH2)2NHCHMe2 13. -N(Me)(CH2)2N(Et)CHMe2 14. CH(Me)N(Me)CH2CHEt2 15. CH(Me)N(Et)CH2CHEt2 16. CH(Me)CH2N(Me)CHEt2 17. CH(Me)CH2N(Et)CHEt2 18. -O-(CH2)2NMeEt 19. N(Me)(CH2)2CHMeEt 20. CH(Me)N(Et)CH2CHMe2 21. CH(Me)CH2N(Et)CHMe2 22. CH(Me)N(Et)(CH2)2CHMe2 23. CH(Me)CH2N(Et)CH2CHMe2 24. CH(Me)(CH2)2N(Et)CHMe2 25. CH(Me)(CH2)3NMe2 26. CH(Me)(CH2)2NEt2 27. -O-(CH2)2NMe2 28. -O-(CH2)2 29. -O-(CH2)3NMe2 30. -N(Me)(CH2)3CHMe2 31. -N(Me)(CH2)2N(Me)CHMe2 32. -N(Me)(CH2)2-O-CHMe2 33. CH(Me)N(Me)CH2CHMeEt 34. CH(Me)N(Et)CH2CHMeEt 35. CH(Me)CH2N(Me)CHMeEt 36. CH(Me)CH2N(Et)CHMeEt 37. N(Me)(CH2)2CHEt2 II Acid addn. salts and pharm. prepns. of I. Hypocholesteremics, blocking cholesterol synthesis. Dose 2-300 mg.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1972</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBByzsjPSS0uSS3Kz1FISS3KLCvmYWBNS8wpTuWF0twMcm6uIc4euqkF-fGpxQWJyal5qSXxzh6mRiamloaOxgQVAABVTR7s</recordid><startdate>19720630</startdate><enddate>19720630</enddate><creator>BORK,KARL-HEINZ,DR</creator><creator>KRAEMER,JOSEF,DR</creator><creator>WATZEL,RUDOLF,DR</creator><creator>BRUECKNER,KLAUS,DR</creator><creator>IRMSCHER,KLAUS,DR</creator><creator>VOEGE,HANS-OTTO,DR</creator><scope>EVB</scope></search><sort><creationdate>19720630</creationdate><title>Cholesterol derivs</title><author>BORK,KARL-HEINZ,DR ; KRAEMER,JOSEF,DR ; WATZEL,RUDOLF,DR ; BRUECKNER,KLAUS,DR ; IRMSCHER,KLAUS,DR ; VOEGE,HANS-OTTO,DR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CH524591A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; ger</language><creationdate>1972</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>BORK,KARL-HEINZ,DR</creatorcontrib><creatorcontrib>KRAEMER,JOSEF,DR</creatorcontrib><creatorcontrib>WATZEL,RUDOLF,DR</creatorcontrib><creatorcontrib>BRUECKNER,KLAUS,DR</creatorcontrib><creatorcontrib>IRMSCHER,KLAUS,DR</creatorcontrib><creatorcontrib>VOEGE,HANS-OTTO,DR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BORK,KARL-HEINZ,DR</au><au>KRAEMER,JOSEF,DR</au><au>WATZEL,RUDOLF,DR</au><au>BRUECKNER,KLAUS,DR</au><au>IRMSCHER,KLAUS,DR</au><au>VOEGE,HANS-OTTO,DR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Cholesterol derivs</title><date>1972-06-30</date><risdate>1972</risdate><abstract>I Cpds. of general formula:- (I) where R' = Cl, OH, (1-18C) O-acyl or (1-4C)O-alkyl and R2 = one of the following:- 1. CH(Me)N(Me)CH2CHMe2 2. CH(Me)CH2N(Me)CHMe2 3. CH(Me)N(Me)(CH2)2CHMe2 4. CH(Me)CH2N(Me)CH2CHMe2 5. CH(Me)(CH2)2N(Me)CHMe2 6. CH(Me)(CH2)2NMe2 7. CH(Me)(CH2)2NEtMe 8. CH(Me)O(CH2)2NMe2 9. O-(CH2)2NEt2 10. -O-(CH2)2 11. -N(Me)(CH2)2CHMe2 12. -N(Me)(CH2)2NHCHMe2 13. -N(Me)(CH2)2N(Et)CHMe2 14. CH(Me)N(Me)CH2CHEt2 15. CH(Me)N(Et)CH2CHEt2 16. CH(Me)CH2N(Me)CHEt2 17. CH(Me)CH2N(Et)CHEt2 18. -O-(CH2)2NMeEt 19. N(Me)(CH2)2CHMeEt 20. CH(Me)N(Et)CH2CHMe2 21. CH(Me)CH2N(Et)CHMe2 22. CH(Me)N(Et)(CH2)2CHMe2 23. CH(Me)CH2N(Et)CH2CHMe2 24. CH(Me)(CH2)2N(Et)CHMe2 25. CH(Me)(CH2)3NMe2 26. CH(Me)(CH2)2NEt2 27. -O-(CH2)2NMe2 28. -O-(CH2)2 29. -O-(CH2)3NMe2 30. -N(Me)(CH2)3CHMe2 31. -N(Me)(CH2)2N(Me)CHMe2 32. -N(Me)(CH2)2-O-CHMe2 33. CH(Me)N(Me)CH2CHMeEt 34. CH(Me)N(Et)CH2CHMeEt 35. CH(Me)CH2N(Me)CHMeEt 36. CH(Me)CH2N(Et)CHMeEt 37. N(Me)(CH2)2CHEt2 II Acid addn. salts and pharm. prepns. of I. Hypocholesteremics, blocking cholesterol synthesis. Dose 2-300 mg.</abstract><edition>1</edition><oa>free_for_read</oa></addata></record>
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title	Cholesterol derivs
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