Acetals and ketals of (6 alpha 17 alpha dihydroxysteroids

New:- Acetals and ketals of 16 alpha, 17 alpha-dihydroxy-steroids of formulae R' is H or acyl R2 is H or acyl R3 is H, acyl or 2-tetrahydropyranyl R4 is OH or acyloxy R5 is H or R4 and R5 together are carbonyl-oxygen X is halogen P is H, lower alkyl or its halogen or carboxy deriv., a monocyclic cycloalkyl, monocyclic aryl, monocyclic aryl-lower alkyl, monocyclic heterocyclic or monocyclic heterocyclic-lower alkyl radical, and Q is the same as P except for H, or P and Q together with the C atom to which they are joined form a cycloalkyl- or monocyclic heterocyclic radical and the 1,2-posn. is opt. unsatd. - Compds. possess an antiphlogistic effect and can be used instead of cortisone for treating acute inflammations and allergic conditions of the eye, skin and mucous membranes.