10-Aminoalkyl-10,11-dihydro-dibenzo(b,f)(1,4)oxazepines - antidepressants with acetylcholine, anti-serotonin and antihistamine activity

(A) Dibenzo (b,f) (1,4) oxazepines Am=an amino group; A=an alkylene residue separating Am and N by at least 2 C atoms. X =O or H2 and at least one of A and B is substd. by NO2, and may be further substd. by alkyl, O-alkyl, CF3, NH2 or halogen. (B) Salts of (I) (C) Intermediates (III) (III) Intermedi...

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1. Verfasser: NAGARAJAN,KUPPUSWAMY,DR
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:(A) Dibenzo (b,f) (1,4) oxazepines Am=an amino group; A=an alkylene residue separating Am and N by at least 2 C atoms. X =O or H2 and at least one of A and B is substd. by NO2, and may be further substd. by alkyl, O-alkyl, CF3, NH2 or halogen. (B) Salts of (I) (C) Intermediates (III) (III) Intermediates for (I) and (II) (I) and (II) - Antidepressants, with anti-acetylcholine, anti-serotonin, antihistamine, antiphlogistic, and local anaesthetic activity. Dose 0.05-0.2 g/day.