Verfahren zur Herstellung von mit einem Aluminiumkation versalzter Pamoasäure

The invention comprises 8-hydroxyquinoline and basic aluminium salts of pamoic acid of general formula and the preparation thereof by reacting pamoic acid or a salt thereof with an aluminium salt or 8-hydroxyquinoline or an acid addition salt thereof preferably in a polar solvent at an elevated temperature.ALSO:Pharmaceutical compositions useful for the treatment of intestinal infections by oral administration, comprise one or more of the 8-hydroxyquinoline dihydroxy aluminium salts of pamoic acid of formula and a pharmaceutical carrier or excipient and optionally a further substance used in the treatment of infections of the intestine, for example, absorbants such as kaolin, an antibiotic such as neomycin, bacitracin and streptomycin, a sulphonamide such as succinylsulphathiazole, phthalylsulphathiazole and formosulphamides, a vitamin of the B group or an antibacterial substance such as a nitrofuranic.