Verfahren zur Herstellung bradykininwirksamer Undeca- und Dodecapeptide

Compounds of the general formula R-L-lysyl-bradykinin in which R is L-ethionyl, L-lysyl, L-lysyl-L-lysyl, D-methionyl, L-phenylalanyl or L-seryl, or represents L-methionyl when the L-lysyl group in the 6-position of bradykinin is replaced by the glycyl-group are prepared by reacting a dipeptide or t...

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Bibliographische Detailangaben
Hauptverfasser:	HEMPEL,REINHARD,DR, SCHROEDER,EBERHARD,DR
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Compounds of the general formula R-L-lysyl-bradykinin in which R is L-ethionyl, L-lysyl, L-lysyl-L-lysyl, D-methionyl, L-phenylalanyl or L-seryl, or represents L-methionyl when the L-lysyl group in the 6-position of bradykinin is replaced by the glycyl-group are prepared by reacting a dipeptide or tripeptide derivative corresponding to R-L-lysyl-, with intermediate protection of the reactive groups not participating in the reaction, with a salt of bradykinin or 6-glycinebradykinin.