Verfahren zur Herstellung eines Pharmaceutikums mit muskelentspannender Wirkung

Verfahren zur Herstellung eines Pharmaceutikums mit muskelentspannender Wirkung

The invention comprises N-methyl-2,2-diphenyl-3-hydroxypropyl carbamate and its preparation by reacting 1,3 propanediol (a) with phosgene or a lower alkyl carbonate, e.g. ethyl carbonate, to give 5,5 diphenyl-1,3 dioxan-2-one, and reacting this with aqueous or anhydrous methylamine, (b) with phosgen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MILAN BERGER,FRANK, JOHN LUDWIG,BERNARD
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention comprises N-methyl-2,2-diphenyl-3-hydroxypropyl carbamate and its preparation by reacting 1,3 propanediol (a) with phosgene or a lower alkyl carbonate, e.g. ethyl carbonate, to give 5,5 diphenyl-1,3 dioxan-2-one, and reacting this with aqueous or anhydrous methylamine, (b) with phosgene or carbophenoxy chloride, and reacting the product with methylamine, or (c) with methyl isocyanate. The compound of the invention possesses muscle relaxant activity.