Procédé pour la préparation de nouveaux prégnènes
A process for the preparation of a "-substituted 6alpha-r steroids of the pregnene, pregnadiene or pregnadiene series, wherein r is an alkyl, aryl, arylalkyl, alkylaryl or a heterocyclic group and wherein r is attached to position 6 through a carbon atom, characterized by treating the correspon...
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| Format: | Patent |
| Sprache: | fre |
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| Zusammenfassung: | A process for the preparation of a "-substituted 6alpha-r steroids of the pregnene, pregnadiene or pregnadiene series, wherein r is an alkyl, aryl, arylalkyl, alkylaryl or a heterocyclic group and wherein r is attached to position 6 through a carbon atom, characterized by treating the corresponding 5alpha, 6alpha-apoxysteroid with a sufficient amount of a grignard reagent and isolating the 5alpha-hydroxy-steroid-6beta-r-substituted and then dehydrating to introduce the unsaturation in a "and isomerize the substituent in 6beta to 6alpha. (Machine-translation by Google Translate, not legally binding) |
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