Verfahren zur Herstellung von N-Monoalkyl-amiden der O,O-Dimethyl-dithiophosphoryl-essigsäure

An N-lower alkylamide of O,O-dimethyl-dithiophosphoryl-acetic acid is obtained by reacting an alkyl or aralkyl ester of O,O-dimethyl-dithiophosphoryl-acetic with a primary lower alkyl amine at a temperature of from -60 DEG C. to 20 DEG C., the term "lower alkyl" being defined as a C1-C5 alkyl radical. The invention also comprises the N-ethylamide of O,O- dimethyldithiophosphorylacetic acid. The reaction may be carried out in the presence of an inert liquid capable of dissolving one or both of the reactants, e.g. water, C1-C5 alcohol, or methylene chloride. The alkyl or aralkyl esters used are preferably the methyl, ethyl or benzyl esters and the preparation of these esters by reacting methyl or ethyl chloracetate or benzyl monobromacetate with the isodium salt of O,O-dimethyl-dithiophosphoric acid is described. Examples are given for the production of the N-methylamide and N-ethylamide of O,O-dimethyl dithiophosphoryl acetic acid. The products have insecticidal properties. Specification 791,824 is referred to. Reference has been directed by the Comptroller to Specifications 886,177 and 886,319.